This book explores the pivotal role of immunofluorescence in advancing diagnostics and research within oral pathology. From identifying autoimmune disorders to unraveling infectious diseases affecting the oral cavity, the application of immunofluorescent techniques offers a powerful toolset for clinicians and researchers alike. The text delves into the principles of immunofluorescence, its integration into oral pathology workflows, and showcases real-world cases where this technique has proven instrumental in unraveling complex oral diseases. As a comprehensive guide, it aims to empower oral healthcare professionals with the knowledge to leverage immunofluorescence for more accurate and timely diagnoses, ultimately enhancing patient care in the realm of oral health.