Problema lecheniya patsientov, stradayushchikh obliteriruyushchim aterosklerozom arteriy nizhnikh konechnostey, yavlyaetsya krayne aktual'noy v sovremennoy sosudistoy khirurgii. Vazhnoe dopolnenie v patogenez obliteriruyushchego ateroskleroza perifericheskikh i koronarnykh arteriy vneslo aktivnoe izuchenie endoteliya arteriy, porodivshee takoe vazhnoe ponyatie kak endotelial'naya disfunktsiya (ED). Izucheniyu ED posvyashchena nastoyashchaya monografiya. V rabote budut rassmotreny biokhimicheskie pokazateli, testy funktsional'nogo sostoyaniya endoteliya, markery vospalitel'nogo otveta organizma i skriningovye markery tromboobrazovaniya s tsel'yu kompleksnogo analiza posleoperatsionnogo statusa patsientov, chto rasshiryaet informatsiyu po diagnostike, vyboru optimal'noy patogeneticheskoy terapii, prognozirovaniyu i profilaktike ryada oslozhneniy, v chastnosti restenoza zony rekonstruktsii arterii. Razvitie restenoza posle khirurgicheskogo lecheniya privodit k neobkhodimosti vypolneniya povtornoy otkrytoy operatsii ili endovaskulyarnoy protsedury. Dannaya monografiya budet polezna spetsialistam v oblasti serdechno-sosudistoy khirurgii, angiologam, a takzhe prepodavatelyam i studentam meditsinskikh vuzov.