Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
PUBLISHER | Springer (04/22/2018) |
PRODUCT TYPE | Paperback (Paperback) |
Description
This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
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Product Format
Product Details
ISBN-13:
9783319825281
ISBN-10:
3319825283
Binding:
Paperback or Softback (Trade Paperback (Us))
Content Language:
English
More Product Details
Page Count:
199
Carton Quantity:
38
Product Dimensions:
6.14 x 0.44 x 9.21 inches
Weight:
0.66 pound(s)
Feature Codes:
Illustrated
Country of Origin:
NL
Subject Information
BISAC Categories
Medical | Oncology - General
Medical | Immunology
Medical | Life Sciences - Molecular Biology
Dewey Decimal:
611.018
Descriptions, Reviews, Etc.
publisher marketing
This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
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List Price $109.99
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$108.89