This book concentrates on ongoing benefits arising out of successfully solving open problems in Number theory of Riemann hypothesis, Polignac's and Twin prime conjectures which were previously unsolved for over 150 years. They are finally solved as Incompletely Predictable problems in 2019. Riemann hypothesis belongs to one of the seven Millennium Prize Problems in mathematics stated by Clay Mathematics Institute on May 24, 2000. It is a useful mental exercise to think of holors as roughly equivalent to the universal "Alphabet of Science" and holor algebra & holor calculus as the universal "Language of Science". Configured as containing useful materials on Medicine, Physiology and Religion, Chapters 1 to 10 as beginning part of this book concentrate on materials related to Alphabet and Language of Science emphasizing its important role in the two innovative 'Spherical Model of Science' and 'Spherical Model of Numbers'. Chapters 11 to 15 contain introductory materials for our three open problems with Chapter 11 explaining the important Fundamental Laws. Chapters 16 to 21 concentrate on describing in layman's terms how rigorous proofs for our three open problems are derived as two complete research papers first published in viXra (and reproduced in Appendix 1 and 2). Chapters 22 to 25 as end part of this book contain materials that speculate on important role of Umbral ("Shadow"), Mathieu and Monstrous Moonshine in String theory potentially uniting Einstein General Relativity and Quantum gravity, and refute a common misconception that solving Riemann hypothesis will lead to E-Commerce apocalypse. The exotic A228186 Hybrid integer sequence published on August 15, 2013 in The On-line Encyclopedia of Integer Sequences (OEIS) is fully outlined in this book.